Selected publications from the lab.

Cancer immune evasion, immunoediting and intratumour heterogeneity.

Nature Reviews Immunology (2025)
In this Review, we discuss the different ways cancer cells evade the immune system and how these mechanisms impact immunoediting and tumour evolution.

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Neoantigen architectures define immunogenicity and drive immune evasion of tumors with heterogenous neoantigen expression

Journal for ImmunoTherapy of Cancer (2024)
Sub-clonal neoantigen expression is linked to poor anti-tumor immunity. We developed a model system to uncover how neoantigen architectures blunt T cell priming in heterogenous tumors.

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HLA Evolutionary Divergence as a Prognostic Marker for AML Patients Undergoing Allogeneic Stem Cell Transplantation

Cancers (2020)
The diversity of the immunopeptidome is critical for anti-tumor immunity. We here studied how the divergence of HLA alleles contributed to the breadth of the immunopeptidome and the success of allogeneic stem cell transplantation in AML.

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Expression levels of HLA-DR in acute myeloid leukemia

Leukemia & Lymphoma (2021)

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Cancer immune evasion, immunoediting and intratumour heterogeneity.

Neoantigen architectures define immunogenicity and drive immune evasion of tumors with heterogenous neoantigen expression